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Top AIDS researcher to leave Montreal for U.S. institute

Although the loss of such a skilled researcher is regrettable, ultimately what Canada needs is a more generous philanthropic culture that supports research. Our federal government alone could never compete with the all the endowment funds at top notch US institutions let alone the resources of US governments.
 
Correct me if I am wrong but I have always understood that although the US does dedicate a larger percentage of GDP towards R&D, isn't the bulk of that through corporate R&D and university research funded by philanthropy. How much of it actually comes from US government funding...and how much of it is non-defence, non-security related?
 
Correct me if I am wrong but I have always understood that although the US does dedicate a larger percentage of GDP towards R&D, isn't the bulk of that through corporate R&D and university research funded by philanthropy. How much of it actually comes from US government funding...and how much of it is non-defence, non-security related?

If the "bulk" of R&D in the US comes from philanthropy, I would like you to provide at least a source if one is available. I have always been under the impression most grants for medical research are distributed through the National Institutes of Health via government grants to universities in the US.
 
There's one thing I think a lot of people misjudge research in the US on: US firms are very good at getting both substantial government and private dollars when it comes to any kind of research. Medical research is a special field, but even outside the field of medical research it seems that when a substantial support network is built by government (many times states and localities will fund the construction of biotech facilities, while the federal government funds grants for the actual research, and then private endowments beef up the offering).

Its this synergy of having well financed government grants and support backed up by private endowments that makes any society a success, regardless of name and location.
 
If the "bulk" of R&D in the US comes from philanthropy, I would like you to provide at least a source if one is available. I have always been under the impression most grants for medical research are distributed through the National Institutes of Health via government grants to universities in the US.

I don't have a source...just said it was my impression. But does most of all the medical R&D come from the NIHs? What about pharmaceutical research for example? I always thought that big pharma managed to pay for a lot of this stuff through their patent rights.
 
There's one thing I think a lot of people misjudge research in the US on: US firms are very good at getting both substantial government and private dollars when it comes to any kind of research. Medical research is a special field, but even outside the field of medical research it seems that when a substantial support network is built by government (many times states and localities will fund the construction of biotech facilities, while the federal government funds grants for the actual research, and then private endowments beef up the offering).

Its this synergy of having well financed government grants and support backed up by private endowments that makes any society a success, regardless of name and location.

Don't get me wrong. I do think that we need to add funds to R&D. However, I always despair at the lack of support beyond the federal government level. For example, there is almost little to no support for scientific research at the provincial level in Canada. And Canadians are extremely stingy when it comes to philanthropic endeavors. If funding was pulled for something like this in the US, you could but that some philanthropist or the state government would step forward. Why can't we have that here?

My personal experience bears out my pessimism. As someone who donates to my alma mater, I am always disappointed that I can never convince many of my friends to do the same. Then again....maybe its me...
 
First, a word on the issue of funding sources:

In the US, the majority of science funding is from neither government, nor philanthropy, but from private industry. Using biological/biomedical research as an example (what I am most familiar with), industry funding accounts for ~60%, federal gov't ~30% (biggest chunk from the NIH), and state gov't and foundations each account for ~5% each (JAMA 294:1333). For foundations, one of the most notable is the Howard Hughes Medical Institute, which funds about $500M a year, compared to NIH's $15-20B. This funding breakdown is not unexpected: the most expensive research is developing new drugs (it takes about $1B to develop one), and the most expensive part of that research, the clinical trials (~70% of the cost), is usually financed and backed by pharmas, so a lot of the money comes directly from industry. I don't have data from the earth sciences and the physical sciences, but while I think the industry portion in those fields would be slightly less than in biomedical, the contribution from private energy companies and materials/computer companies would still be very high.

The total science funding in the US, as of 2008, is slightly less than $50B, compared Canada's $600M USD. However, the US amount is 1.5% of its GDP, whereas Canada's is 3%, so proportionally, Canada is already funding science more than the US (it is in his current budget that Obama proposes increasing the science funding to 3% of GDP over the next 10 years). Thus, while science funding in Canada is definitely small compared to the US, it is not for want of trying.

And Keithz, the reason Canadian provinces don't contribute "as much" to science funding as the American states is probably because the provinces are less financially independent/self-supporting in our system. However, MaRS is a perfect example of a research initiative where the provincial government has a significant stake. In fact, it was under the Harris/Eves government that Ontario injected significant money ($1B over 10 years) into this and a few other sci/tech initiatives, an amount that even Nature commented is un-Canadianly large (Nature 425:104). So, the provinces are certainly doing their share.

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Back to the OT of Sekaly:
If anyone actually bothered to read the actual news, you would realize that he is not uprooting and moving shop, as the CBC would like you to believe. Half his group is in fact staying in Montreal, and he will be spending 1/3 of his year in Canada. Moreover, he has been in discussion with the US institute for the past 3 years, after his discovery starts getting ready for the costly translation from the bench to the clinic, something that few places outside of the US and UK are able to do. Of course, "losing" a reputable scientist (for 2/3 of the year) to the US is a loss for Canada, but the brain drain, and the reverse brain drain, has been going on for decades, through Liberal and Tory governments. In the past couple of years alone I have personally known three American scientists, perhaps not of Sekaly's calibre but doing good research nonetheless, and all in the basic sciences, who landed positions in Canada and moved up north. I cannot predict if there will now be a sudden "exodus" of Canadian talents to the "Promised Land" down south, but this story has certainly been overblown to make fodder for Liberal zealots.

Personally I question the merits of the Tories' (and the tricouncil's) shift of funding focus from principle investigator grants to infrastructure and student scholarships/fellowships, but to claim that they are destroying Canadian science is absurd. And to believe that Ignatieff is a messiah who will miraculously "save" Canadian science (and everything else in Canada) reeks of insanity.
 
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^ Informative post. Thanks for that. Any links you have on funding would be appreciated. I have long suspected as much. The number of foundations, endowments, etc. in the US always blows my mind. And I have always understood those institutions to be the real backbone of scientific advancement in the US....something Canada has lagged in replicating here (even U of T's endowments pales in comparison to some private research universities like Harvard or MIT or Caltech - and more so when the student population size is taken into account). That does not even take into account university tuition. Our governments fund tuition far more than the US....whereas US governments tend to throw money at research in their universities.

In this particular case I am deeply suspicious of The Star's agenda when it comes to putting out the news. Some days they are as bad as Fox News in the US. Ditto for the National Post sometimes. The CBC though is a little better....but some times the do slip up in their standards...and this story is one.
 
^ Actually, my point was that even in the US, foundations account for only a small (albeit significant) percentage of science funding (5%). The industry funds the lion's share of research, but that's mostly at the applied level and happens mostly in pharmas and biotechs themselves, or hospitals if it's a clinical trial. The NIH still funds the majority of basic research happening at academic institutions. University/department endowments are usually used to supplement the NIH grants, and they do sometimes give startup grants to new investigators who are still trying to get outside funding, or transition funds for those who run out of funding, but the majority of funding for researchers at universities and institutions are still from NIH grants. The foundations in Canada (like the cancer and heart societies) do fund significant research too (not sure if it's comparable to their counterparts in the US though, don't have the data), but it is for sure true that Canada doesn't have the likes of HHMI, Broad or Gates foundations (though these foundations do fund some Canadian researchers too). So, the situation in America really isn't that the 5% of foundation funding forms the backbone of research advancement; the NIH is still by far the greatest source of that. It's more that, there are just lots more funding everywhere so that more research can be done, especially the applied research which is done in industry. However, even in the case of industry, many pharmas are realizing that they are not really getting as much from their in house R&D as they hoped they would get from the amount of money they are spending. They are increasingly turning towards basic researchers at universities for ideas and discoveries, and trying to foster that by contributing to nonprofits or setting up their own foundations to award grants, so the percentage of industry funding could gradually decrease and that of foundation funding could increase.

The funding breakdown can be found in the article in JAMA 294:1333. Here's a link to the article. A lot of the other numbers are from what I took down at talks by industry or foundation reps, so I don't really have links for them.
 
Every university's endowment pales in comparison to Harvard. It isn't a very fair yardstick.

I think this comes down to a mostly cultural difference between Canadians and Americans, as well as due to differences in size of government/taxation.

It seems that Canadians are simply less philanthropic than Americans. There certainly is less inequality in terms of wealth, which means there are less of the very richest, the people who can form the backbone of a lot of philanthropy (often through their foundations). We also seem to see a larger role for the state in society, whereas America seems to have some real hang-ups in that regard (note how much the word 'socialism' is used to describe any and every government intervention). We are also less religious. I don't know if theists are more likely to donate time or money, but I suspect it is so.

The other argument is that we are taxed to a greater extent, and thus we have less disposable income to donate. I'm not sure this is a driving factor--if anything, a higher marginal tax rate means you give up less after tax income for every dollar you donate.
 
^ I have read somewhere that per capita Americans donate more time and personal income than anyone else. This would in part explain their government's stinginess when it comes to foreign aid and/or grants for services at home.

I'd agree that we on the other hand rely on government to do the bulk of the heavy lifting. And that's probably the challenging part when it comes to scientific research. Government bureaucrats aren't necessarily the best when it comes to picking winners and losers in the science funding lottery. And the best projects are often too expensive for just the federal government to fund alone. ITER was a good example of this.
 
^Actually, who gets funding in science (at least in life science, but I am pretty sure about the other fields as well) is almost never decided by government bureaucrats. NIH, NSF, NSERC, CIHR, or any other of these funding agencies decide who gets funding by the decision of the peer review process by fellow scientists based on the scientific merit of the proposals. However, it is somewhat true that the general funding direction (eg. more for the biomedical fields vs more for the physical sciences) and the direct funding for multinational "Big Science" projects are somewhat political decisions by the Executive (still not so much the bureaucrats). Which is why all the more important it is for countries to have competent science ministes/advisors to advise the Presidents/Prime Ministers on which direction to go.

I don't remember the specific details for ITER, but I think a large part of the withdrawal decision was because Canada lost the hosting competition to Europe. A similar situation is Austria's recent withdrawal from CERN in the interest of focusing on other fields.
 

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