I thought of the scenario where the PC's win a majority, but Ford loses his seat.
Would someone step aside for Ford to run in an immediate by-election. It couldn't be someone from Toronto, or maybe even the immediate GTA, since there would be the risk of losing that by-election as well. The scenario along your lines would be to try and replace the leader at that time. My reading of the PC constitution says that a leadership review can only be triggered if they don't form government. Thus, this could not be done, unless they somehow first revise the constitution. I could see some interesting politics occur in this scenario.