Well i always like a little house but the girls always love that top 40 crap so maybe somewhere which mixes the 2.
in that case, you might want to try a club like MINK which is a "meat factory" IMO. the girls are hot and the music is split between house and hip hop / top 40. the age of this club is mixed but is mostly made up of people in their mid 20's.
you can also try a club like PEARL LOUNGE which is like mink but has more people in their early 20's. more thugs here though.
BUDO is also a nice setup with a Buddhist decor. very hot girls,
house and top 40. more mature atmosphere.
now, the best for last, FILM LOUNGE. film lounge is IMO one of the best club atmospheres in toronto. the club its self is hidden (a la new york style). the bouncers have very boring jobs here because there are no thugs. the music is all house based. no top 40. the clients are mature mid 20's and up. if you are 40 years old you can still feel comfortable in this club. everyone is so nice. you have a better chance of wining 30 million dollars on super seven than seeing a fight here.
the girls are very extremely hot.
the club doesn't really hit capacity till 2:30am - 3:00am. don't go there and expect to have a good time at 12:00am. the dj's are live and are spinning real vinyl. you will hear the latest house music here.
the club has an intimate lounge area, a big dance floor and a vip section. even though the club is based on house music, there is a dress code in effect. they don't wanna be labeled as a rave club and get all the negative discrimination that comes along with that title.
the club is safe, fun and full of energy which continues till 7:00am.