There's no such thing as "we'll worry about the ground level after we've addressed all our other problems". When it comes to highrises, whatever gets built now is essentially permanent. There is no fixing it later.
To build on this point, Niagara's keen interests here actually relate to intensifying its permanent, year-round population; and boosting its economy via tourism, less in the sense of attracting more tourists (though they'll happily take that) but rather in increasing overnight and multi-day stays and increasing per capita spend.
To do so not only requires creating a walkable, pleasant space, especially around a key new hotel and key new residence; but also linking that streetscape and integrating that walking, cycling, transit experience with adjacent areas and tourist locales.
This area needs a slew of things beyond nice streetscape and good podium/ground level treatments, but that is a critical start.
If I were to look at what's missing, I'd start with a high-quality urban supermarket to serve the needs of the residential population, leaning upmarket so it also serves non-Canadian tourists to get their maple syrup and other Canadian food'isms in as well.
Follow that with a flagship LCBO showcasing Niagara wine; some additional good quality restos, particularly offering the patio experience; and then something both tourists and locals could use, shift the local multiplex to the Clifton Hills to Fallsview area; and make it fit the tourist bill; licensed bar, licensed cinemas, at least 1 IMAX, at least 3 VIP screens, creating something for locals, but also that all important experience for tourists on a rainy day or when the kids are having an 'I'm bored' moment.
It's important to build towards a community vision 20-30 years out.
Either GO needs to come one station closer, using the old ROW, or LRT needs to arrive at some point likely Bridge (GO Stn) to Victoria to Ferry/Lundy's Lane.
To justify that the development has to appear, and it has to foster a walking, cycling, transit culture. If everyone just drives to the big boxes towards the edge of town or over to the mall in St. Kitts, then this fails to contribute to a positive course of development for the area.